Distinct neuronal processes in the ventromedial prefrontal cortex mediate changes in attention load and nicotine pro-cognitive effects in male rats
Caroline Vouillac-Mendoza, Nathalie Biendon, Sandra Dovero, Karine Guillem
Front. Neural Circuits. 2025-03-07
10.3389/fncir.2025.1540975

Bidirectional relationship between attentional deficits and escalation of nicotine intake in male rats
Caroline Vouillac-Mendoza, Serge H. Ahmed, Karine Guillem
Psychopharmacology. 2024-05-14
10.1007/s00213-024-06604-x

Knowledge by omission: the significance of omissions in the 5-choice serial reaction time task
Caroline Vouillac-Mendoza, Audrey Durand, Serge H. Ahmed, Karine Guillem
Psychopharmacology. 2024-03-06
10.1007/s00213-024-06564-2

Large‐scale brain correlates of sweet versus cocaine reward in rats
Magalie Lenoir, Sylvia Navailles, Youna Vandaele, Caroline Vouillac‐Mendoza, Karine Guillem, Serge H. Ahmed
Eur J of Neuroscience. 2022-12-01
10.1111/ejn.15879

Altered neuronal activity in the ventromedial prefrontal cortex drives nicotine intake escalation
Myriam Abarkan, Giulia R. Fois, Caroline Vouillac-Mendoza, Serge H. Ahmed, Karine Guillem
Neuropsychopharmacol.. 2022-08-30
10.1038/s41386-022-01428-9

Large-scale brain correlates of sweet versus cocaine reward in rats
Magalie Lenoir, Sylvia Navailles, Youna Vandaele, Caroline Vouillac-Mendoza, Karine Guillem, Serge H. Ahmed
Preprint bioRxiv. 2022-06-02
10.1101/2022.06.01.494287

Probing the decision-making mechanisms underlying choice between drug and nondrug rewards in rats
Youna Vandaele, Magalie Lenoir, Caroline Vouillac-Mendoza, Karine Guillem, Serge H Ahmed
eLife. 2021-04-26
10.7554/eLife.64993

Habitual Preference for the Nondrug Reward in a Drug Choice Setting
Youna Vandaele, Karine Guillem, Serge H. Ahmed
Front. Behav. Neurosci.. 2020-05-25
10.3389/fnbeh.2020.00078

Reorganization of Theta Phase-Locking in the Orbitofrontal Cortex Drives Cocaine Choice Under the Influence
Karine Guillem, Serge H Ahmed
Sci Rep. 2020-05-15
10.1038/s41598-020-64962-w

Relapse to cocaine use persists following extinction of drug-primed craving
Paul Girardeau, Sylvia Navailles, Audrey Durand, Caroline Vouillac-Mendoza, Karine Guillem, Serge H. Ahmed
Neuropharmacology. 2019-06-01
10.1016/j.neuropharm.2019.05.036

A neuronal population code for resemblance between drug and nondrug reward outcomes in the orbitofrontal cortex
Karine Guillem, Serge H. Ahmed
Brain Struct Funct. 2018-12-11
10.1007/s00429-018-1809-8

Pre-trial cocaine biases choice toward cocaine through suppression of the nondrug option
Luana Freese, Audrey Durand, Karine Guillem, Serge H. Ahmed
Pharmacology Biochemistry and Behavior. 2018-07-01
10.1016/j.pbb.2018.07.010

Incubation of Accumbal Neuronal Reactivity to Cocaine Cues During Abstinence Predicts Individual Vulnerability to Relapse.
Karine Guillem, Serge H Ahmed
Neuropsychopharmacology. 2017-09-18
10.1038/npp.2017.224

Neuronal representation of individual heroin choices in the orbitofrontal cortex
Karine Guillem, Viridiana Brenot, Audrey Durand, Serge H. Ahmed
Addiction Biology. 2017-07-13
10.1111/adb.12536

Preference for Cocaine is Represented in the Orbitofrontal Cortex by an Increased Proportion of Cocaine Use-Coding Neurons.
Karine Guillem, Serge H. Ahmed
Cereb. Cortex. 2017-01-04
10.1093/cercor/bhw398

Abstinence from cocaine and sucrose self-administration reveals altered mesocorticolimbic circuit connectivity by resting state MRI.
Hanbing Lu, Qihong Zou, Svetlana Chefer, Thomas J. Ross, D. Bruce Vaupel, Karine Guillem, William P. Rea, Yihong Yang, Laura L. Peoples, Elliot A. Stein
Brain Connectivity. 2014-09-01
10.1089/brain.2014.0264

Escalation of cocaine intake and incubation of cocaine seeking are correlated with dissociable neuronal processes in different accumbens subregions.
Karine Guillem, Serge H. Ahmed, Laura L. Peoples
Biological Psychiatry. 2014-07-01
10.1016/j.biopsych.2013.08.032

Coordinated Recruitment of Cortical-Subcortical Circuits and Ascending Dopamine and Serotonin Neurons During Inhibitory Control of Cocaine Seeking in Rats.
Sylvia Navailles, Karine Guillem, Caroline Vouillac-Mendoza, Serge H. Ahmed
Cereb. Cortex. 2014-05-28
10.1093/cercor/bhu112

Neurobiology of addiction versus drug use driven by lack of choice.
Serge H Ahmed, Magalie Lenoir, Karine Guillem
Current Opinion in Neurobiology. 2013-08-01
10.1016/j.conb.2013.01.028

Sugar addiction: pushing the drug-sugar analogy to the limit.
Serge H. Ahmed, Karine Guillem, Youna Vandaele
Current Opinion in Clinical Nutrition and Metabolic Care. 2013-07-01
10.1097/mco.0b013e328361c8b8

Dorsolateral caudate nucleus differentiates cocaine from natural reward-associated contextual cues.
H.-S. Liu, S. Chefer, H. Lu, K. Guillem, W. Rea, P. Kurup, Y. Yang, L. Peoples, E. A. Stein
Proceedings of the National Academy of Sciences. 2013-02-19
10.1073/pnas.1207531110

Discriminative inhibitory control of cocaine seeking involves the prelimbic prefrontal cortex.
Claudia Mihindou, Karine Guillem, Sylvia Navailles, Caroline Vouillac, Serge H. Ahmed
Biological Psychiatry. 2013-02-01
10.1016/j.biopsych.2012.08.011

fMRI response in the medial prefrontal cortex predicts cocaine but not sucrose self-administration history.
Hanbing Lu, Svetlana Chefer, Pradeep K. Kurup, Karine Guillem, D. Bruce Vaupel, Thomas J. Ross, Anna Moore, Yihong Yang, Laura L. Peoples, Elliot A. Stein
NeuroImage. 2012-09-01
10.1016/j.neuroimage.2012.05.076

Drug specificity in extended access cocaine and heroin self-administration.
Magalie Lenoir, Karyn Guillem, George F. Koob, Serge H. Ahmed
Addiction Biology. 2011-10-13
10.1111/j.1369-1600.2011.00385.x

Acute effects of nicotine amplify accumbal neural responses during nicotine-taking behavior and nicotine-paired environmental cues.
Karine Guillem, Laura L. Peoples
PLoS ONE. 2011-09-22
10.1371/journal.pone.0024049

Nicotinic acetylcholine receptor β2 subunits in the medial prefrontal cortex control attention.
K. Guillem, B. Bloem, R. B. Poorthuis, M. Loos, A. B. Smit, U. Maskos, S. Spijker, H. D. Mansvelder
Science. 2011-08-11
10.1126/science.1207079

Varenicline effects on cocaine self administration and reinstatement behavior.
Karine Guillem, Laura L. Peoples
Behavioural Pharmacology. 2010-03-01
10.1097/fbp.0b013e328336e9c5

Progressive and lasting amplification of accumbal nicotine-seeking neural signals.
K. Guillem, L. L. Peoples
Journal of Neuroscience. 2010-01-06
10.1523/jneurosci.2820-09.2010

Orbitofrontal and insular cortex: neural responses to cocaine-associated cues and cocaine self-administration.
Karine Guillem, Alexxai V. Kravitz, David E. Moorman, Laura L. Peoples
Synapse. 2010-01-01
10.1002/syn.20698

Voluntary nicotine consumption triggers in vivo potentiation of cortical excitatory drives to midbrain dopaminergic neurons.
S. Caille, K. Guillem, M. Cador, O. Manzoni, F. Georges
Journal of Neuroscience. 2009-08-19
10.1523/jneurosci.2950-09.2009

Monoamine oxidase inhibition dramatically prolongs the duration of nicotine withdrawal-induced place aversion.
Karine Guillem, Caroline Vouillac, George F. Koob, Martine Cador, Luis Stinus
Biological Psychiatry. 2008-01-01
10.1016/j.biopsych.2007.04.029

The role of accumbal hypoactivity in cocaine addiction.
L. L. Peoples, A. V. Kravitz, K. Guillem
The Scientific World JOURNAL. 2007-01-01
10.1100/tsw.2007.266

Monoamine oxidase A rather than monoamine oxidase B inhibition increases nicotine reinforcement in rats.
Karine Guillem, Caroline Vouillac, Marc R. Azar, Loren H. Parsons, George F. Koob, Martine Cador, Luis Stinus
European Journal of Neuroscience. 2006-12-01
10.1111/j.1460-9568.2006.05217.x

Monoamine oxidase inhibition dramatically increases the motivation to self-administer nicotine in rats.
K. Guillem
Journal of Neuroscience. 2005-09-21
10.1523/jneurosci.2139-05.2005