The dual hit hypothesis of schizophrenia
, Cyprien Guerrin
.
10.33612/diss.791866719

Increased cocaine self-administration and prefrontal cortical dysregulation of glutamatergic and GABAergic signaling in a rat model for sensory processing sensitivity
Rick Hesen, Francesca Mottarlini, Lucia Caffino, Sophie Fennema, Susanna Parolaro, Cyprien G. J. Guerrin, Boris B. Quednow, Fabio Fumagalli, Michel M.M. Verheij, Judith R. Homberg
. 2025-10-29
10.1101/2025.10.28.685083

Apomorphine susceptibility and prenatal infection alter neurodevelopment, synaptic density and anticipatory behavior in rats
Kate Witt, Meyrick Kidwell, Janine Doorduin, Erik.F.J. de Vries, Iris E. Sommer, Darren J. Day, Bart A. Ellenbroek, Cyprien G.J. Guerrin
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 2025-10-01
10.1016/j.pnpbp.2025.111490

Characterization of [11C]DASB and [18F]FE-PE2I using microPET imaging in SERT and DAT knockout rats
Cyprien G.J. Guerrin, Debbie R.M. Tesselaar, Emile E. Zweistra, Anna Cabiscol-Claveria, Bieneke Janssen, Janine Doorduin, Arnt F.A. Schellekens, Jan Booij, Judith R. Homberg
Nuclear Medicine and Biology. 2025-09-01
10.1016/j.nucmedbio.2025.109055

Precision medicine in substance use disorders: Integrating behavioral, environmental, and biological insights
Cyprien G.J. Guerrin, Debbie R.M. Tesselaar, Jan Booij, Arnt F.A. Schellekens, Judith R. Homberg
Neuroscience & Biobehavioral Reviews. 2025-09-01
10.1016/j.neubiorev.2025.106311

Prospective Intergenerational Consequences of Paternal Stress Experiences on Offspring Immune Health
Cyprien G. J. Guerrin, Mari Trompke, Terence Y. Pang
Epigenetics in Biological Communication. 2024-01-01
10.1007/978-3-031-59286-7_10

Prenatal infection and adolescent social adversity affect microglia, synaptic density, and behavior in male rats
Cyprien G.J. Guerrin, Kavya Prasad, Daniel A. Vazquez-Matias, Jing Zheng, Maria Franquesa-Mullerat, Lara Barazzuol, Janine Doorduin, Erik F.J. de Vries
Neurobiology of Stress. 2023-11-01
10.1016/j.ynstr.2023.100580

Maternal infection during pregnancy aggravates the behavioral response to an immune challenge during adolescence in female rats
Cyprien G.J. Guerrin, Erik F.J. de Vries, Kavya Prasad, Daniel A. Vazquez-Matias, Lesley E. Manusiwa, Lara Barazzuol, Janine Doorduin
Behavioural Brain Research. 2023-08-01
10.1016/j.bbr.2023.114566

Social adversity during juvenile age but not adulthood increases susceptibility to an immune challenge later in life
Cyprien G.J. Guerrin, Janine Doorduin, Kavya Prasad, Daniel A. Vazquez-Matias, Lara Barazzuol, Erik F.J. de Vries
Neurobiology of Stress. 2023-03-01
10.1016/j.ynstr.2023.100526

Immune Activation in Pregnant Rats Affects Brain Glucose Consumption, Anxiety-like Behaviour and Recognition Memory in their Male Offspring
Cyprien G. J. Guerrin, Alexandre Shoji, Janine Doorduin, Erik F. J. de Vries
Molecular Imaging and Biology. 2022-04-05
10.1007/s11307-022-01723-3

A single dose of ketamine cannot prevent protracted stress-induced anhedonia and neuroinflammation in rats
Rodrigo Moraga-Amaro, Cyprien G. J. Guerrin, Luiza Reali Nazario, Bruno Lima Giacobbo, Rudi A. J. O. Dierckx, Jimmy Stehberg, Erik F. J. de Vries, Janine Doorduin
Stress. 2022-01-02
10.1080/10253890.2022.2045269

P.0455 Maternal immune activation reduced recognition memory and increased anxiety-like behaviour and brain metabolism in the rat offspring
C. Guerrin, J. Doorduin, E.F.J. De Vries
European Neuropsychopharmacology. 2021-12-01
10.1016/j.euroneuro.2021.10.428

The dual hit hypothesis of schizophrenia: Evidence from animal models
Cyprien G.J. Guerrin, Janine Doorduin, Iris E. Sommer, Erik F.J. de Vries
Neuroscience & Biobehavioral Reviews. 2021-12-01
10.1016/j.neubiorev.2021.10.025